THE SIGNAL
BLOG BY SIGNANT HEALTH
Expert Insights on Clinical Research Topics
Explore a diverse range of clinical research topics on The Signal, our blog featuring expert insights and opinions from our clinical, medical, digital health, science, and eClinical technology solution thought leaders. Topics include outcomes measurement science and best practices, trial design and evidence generation strategies, approaches to optimizing endpoint reliability, and more.
Methodology
The Scientific Evolution from NASH to MASH: Understanding the Rationale Behind the Nomenclature Change
Anthony T. Everhart, MD
Feb 16, 2026
Cognitive Assessments
Web-based CDR System: Precision Without Compromise
Helen Brooker & Pascal Goetghebeur
Jan 20, 2026
Clinician Ratings
4 Common Rater Concerns During Placebo Response Mitigation Training... and How to Address Them
Joan DeGeorge, Erica Appleman, Sayaka Machizawa, Gary Sachs
Nov 20, 2025
Data Analytics
From Data Signals to Endpoint Success: How Integrated Analytics and Rater Training Transformed an Atopic Dermatitis Trial
Maria Visser, Todd Everhart, Marcela Roy, Dr Alan Kott
Oct 31, 2025
eCOA
Smart Cells, Smarter Trials: How CAR-T Cell Therapy and Digital Health Are Changing Cancer Care
Viani Figueroa Vazquez, Anthony T. Everhart
Sep 18, 2025