Clinical research investigating novel treatments or therapies for Central Nervous System (CNS) diseases is as complicated and nuanced as are the conditions
eCOA & Electronic Clinician Ratings
With dozens of built-in electronic neurology and psychiatry clinical outcome assessments, our eCOA platform minimizes rater errors by applying internal logic, edit checks, audio/video recording capability, and on-screen guidance to facilitate ensure accurate, reliable COA data.
Placebo Response Mitigation
Limit the impact of placebo response on study success through protocol-specific training for investigators, site staff, and patients delivered by Signant clinicians. Our training is proven to lower the impact of placebo response, driving cleaner assessments of treatment effects.
Rater Training & Certification
Leveraging our direct experience in CNS trials, our experts qualify, train, certify, and recalibrate raters throughout your studies to ensure consistency, accuracy, and standardization. Our technology enables gatekeeping of raters by qualification status to further safeguard study data.
Blinded Data Analytics
A must-have component to any CNS study, Signant’s unique analytics solution blends proprietary algorithms with clinical/statistical interpretation and analysis, helping study teams proactively mitigate data quality risks at all relevant levels of your study.
Central Review
Access a network of specialized, experienced raters who perform independent reviews of recorded assessments to validate scoring and administration consistency and accuracy, ensuring COA data reliability.
Scientific Consulting
Our unrivaled and highly-experienced team of CNS science and medicine professionals, as well as clinical trial technology and operations experts, actively partner with study teams from launch to closeout to optimize clinical data quality and CNS study outcomes.