eCOA 

An eCOA clinical trial uses technology to accelerate clinical data collection and ensure proper data quality analyses. More sponsors are choosing eCOA for their clinical trials to gain a better understanding of how patients feel and function in near real-time.

The difference between Electronic Clinical Outcome Assessment (eCOA) and Electronic Patient-Reported Outcome (ePRO) is that ePRO systems are a type of eCOA. Clinical trial patients often use eCOA system technologies on mobile devices to remotely send their ePRO symptoms and experience directly to site staff. Other types of COA include Electronic Performance Outcome ePerfO, Electronic Clinician-Reported Outcome (eClinRO), and Electronic Observer-Reported Outcome (eObsRO).

Signant’s instrument library contains over 50 instruments commonly used in clinical trials. In many cases, we offer pre-approved versions, which means an author review step is not required. Additionally, our library instruments are designed using best practices and are pre-validated, so they do not require additional testing when implemented in a new clinical study, saving you time and ensuring high quality.

Signant proudly provides expert consulting with our solutions, like eCOA. We believe that combining our advanced technology with scientific and clinical expertise properly sets studies up for success. Our focus on protecting data quality along with our credibility among authors and license holders helps us successfully navigate electronic implementations. With a deep understanding of regulatory needs, our team can help steer clients throughout their clinical trials.

Yes. Signant SmartSignals eCOA includes the ability to implement the PROMIS CAT seamlessly alongside conventional PROMS. Choose from more than 20 domains including anxiety, depression, fatigue, sleep disturbance, pain interference, physical function, and social function. For more information, read our PROMIS CAT brochure and white paper.