Duchenne Muscular Dystrophy
Trial Solutions

Improve Clinical Ratings Accuracy & Consistency

 Inconsistencies in assessment administration and scoring can lead to difficulties interpreting the data. Signant's Rater Training program focuses on qualifying raters and standardizing assessment technique to reduce inter- and intra-rater variability as well as mitigate placebo response. Video capture and expert reviews by our in-house DMD experts can also be leveraged to ensure endpoint reliability.

 

Maximize Study Supply Chain Efficiency

Signant’s RTSM solution can be implemented rapidly in just one to four weeks and utilizes a unique algorithm to dynamically optimize IP usage for global studies. We focus on reducing waste, reconciliation/returns efforts, and the number of shipments required to ensure compounds for these studies do not go to waste through overages or expiration.

 

Optimize Endpoint Reliability

Guide investigative staff through proper ClinRO assessment technique using our enhanced clinician ratings platform. Automated scoring, branching logic, and built-in edit checks help reduce errors. When paired with Blinded Data Analytics, we can proactively monitor data in real-time, creating opportunities to mitigate risks before they impact your study data. 

 

Leverage Our DMD Research Experts

From consulting on outcome measure selection and implementation to reducing burdens on sites and patients, Signant’s in-house experts will help you navigate common DMD challenges throughout the study lifecycle. Talk through your protocol with our clinical science and medicine experts experienced in neuromuscular, rare disease, and pediatric studies.