Revolutionize Your Clinical Trial Data Quality with Audio-Digital Surveillance

How reliable are clinician ratings in clinical trials? This study explores the impact of audio-digital ratings surveillance as a data quality monitoring strategy in major depressive disorder (MDD) clinical trials.

Learn how paired site-based and site-independent scores revealed high concordance, improved rater performance, and predicted treatment response rates across five trials.

For example, this research demonstrates that audio-digital recordings of site-based clinician interviews yield highly reliable paired scores with minimal discordance. This surveillance strategy effectively identifies rating "outliers" while providing a high predictive value (91.2%) for replicating treatment response rates across five clinical trials.

Discover how a precision-driven quality assurance methodology using PureSignal Analytics can strengthen your site-based results and protect against potential functional unblinding.

This article was originally published in Contemporary Clinical Trials Communications 14 (2019) by Steven D. Targum and Christopher J. Catania.