Movement Disorders

Partner with Signant Health to optimize your movement disorder trials and achieve accurate, reliable endpoint data you can trust. 

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Transform Your Movement Disorder Studies

In the complex world of movement disorder trials, you need a partner who understands the unique challenges you face.
Signant's specialized solutions have been refined through 25 years of experience with sponsors and CROs, delivering measurable improvements in:
 
  • Data reliability - Reduce variability in movement disorder assessments
  • Patient engagement - Keep participants enrolled even in long term studies
  • Site performance - Identify and address site-related quality issues before they negatively affect results
  • Study timelines - Accelerate your path to approval with efficient trial execution
Our deep expertise in Parkinson's, Huntington's, dystonia, and other movement disorders means we solve problems others can't even identify.
 

Key Solutions for Movement Disorder Trial Success

Patient Recruitment & Retention

Progressive symptoms make participant engagement challenging in movement disorder studies. Our patient-centric technology simplifies participation and reduces burden, resulting in higher retention rates.

Data Collection and Management

Inconsistent movement symptom assessment compromises study outcomes. Our standardized electronic data capture includes built-in quality controls to ensure accurate measurement across all sites.

Remote Visits

Our technology captures real-world symptom data while reducing travel burden for patients with mobility limitations, allowing you to maintain data integrity without requiring frequent clinic visits.

Ensure Endpoint Reliability

Our enhanced clinician ratings platform guides investigative staff through proper assessment technique with automated scoring and built-in edit checks that significantly reduce errors. When paired with PureSignal Analytics, we proactively monitor COA data in real-time, creating opportunities to mitigate quality risks before they impact your signal detection capability.

Improve Ratings Accuracy

Movement disorder endpoints rely on specialized scales, but scoring inconsistencies can compromise data quality. Our Rater Training program standardizes assessment techniques and reduces variability across sites.

Adaptive Trial Designs

Our agile technologies support protocol adjustments and enable data-driven decisions throughout your study, helping you respond to emerging insights without compromising quality.

Video Capture & Independent Expert Review

Extensive network of movement disorder experts allow for adjudication, independent scoring, and local language site remediation among other things.

Extensive Pediatrics Expertise

For movement disorder studies involving pediatric populations, Signant has unparalleled experience in helping design and conduct trials that sensitively and accurately capture needed assessments.

Our Movement Disorder Experience

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250+ TRIALS

6.8K+ SITES

44 COUNTRIES

23.3K+ PATIENTS

Movement Disorder Research Excellence: Proven Across 250+ Trials

Signant brings specialized expertise to movement disorder clinical trials, with proven solutions for accurate assessments, enhanced patient engagement, and improved data quality across multiple indications.

Neurodegenerative Disorders

Cerebellar Disorders

Neurological Conditions with Movement Symptoms

Hyperkinetic Disorders

Sleep-Related Movement Disorders

Other Movement Disorders

Research Innovations
Electronic Diary for Parkinson's Disease Motor Symptoms 

We developed a patient-centered electronic version of the Hauser motor symptom diary for Parkinson's disease, optimizing the user experience for those with motor challenges. Through interviews with 10 PD patients, we established key design principles including landscape format, single 30-minute intervals, and touch-friendly components.

Presented at MDS 2024 | Pereira M, Byrom B, Rektoroprodic P, Fredane L

Our Science & Medicine Experts Lead With Excellence

Our specialized movement disorders studies benefit from comprehensive support through our exceptional clinical, operational, electronic clinical outcome assessment, and technical leadership teams.

The expertise of our clinical vice presidents in neurology, rare diseases, and data analytics ensures that our movement disorders research maintains the highest standards of scientific integrity and patient care.

Explore Resources

Case Study

How Central Ratings Improved a Pivotal
TD Trial

VIEW CASE STUDY
WEBINAR

Clinical Rating Methods Applied to Movement Disorder Studies

WATCH NOW
POSTER

Improving Assessment Accuracy in Tourette Syndrome

VIEW POSTER

Ready to Optimize Your Movement Disorder Trials?

Discover how our specialized solutions have helped sponsors achieve up to 40% greater signal detection. Let's discuss your protocol.