AI‑Targeting of Rating Assessments | Central Review for ClinRO Quality

Closing the coverage gap

In most CNS trials, only 10-20% of assessment data ever gets reviewed by experts. That means up to 90% of sessions, along with potential scoring errors, protocol deviations, or missed clinical signals go completely unchecked.

Our solution changes that. It flags issues across 100% of your study data using AI, then routes only the highest-risk sessions to your expert reviewers for confirmation.

You get full visibility, verified by humans, without adding workload.

A new standard for comprehensive data confidence

Signant's advanced AI-targeting transforms clinical assessment quality assurance by delivering 100% data coverage with 100% human verification of flagged assessments. This AI-powered solution enhances industry-standard central review by flagging potential issues across all assessments, enabling expert reviewers to focus their attention precisely where it matters most – without requiring additional human resources.

With our solution, you're not just improving quality assurance – you're setting a new standard for unprecedented endpoint reliability that positions your CNS trials for success.

Data & A/V Capture

Clinical interactions captured during visits

Scores and rating interviews captured using RaterStation® or transmitted to Signant Health

Transcription output to AI-targeting

Derive interview transcripts from A/V recordings

Transcription output to AI-targeting

AI-Targeting

Automated transcript analysis

Identify ratings with possible administration and scoring issues

Targeted Central Review

Clinical experts assess flagged ratings of concern

Human review of flagged ratings

Final Quality Determination

Central Reviewer provides final review outcome, remediation, and commentary (as applicable)

Final human-qualified reviewed output

Data & A/V Capture

Clinical interactions captured during visits

Scores and rating interviews captured using RaterStation® or transmitted to Signant Health

Transcription output to AI-targeting

Derive interview transcripts from A/V recordings

Transcription output to AI-targeting

AI-Targeting

Automated transcript analysis

Identify ratings with possible administration and scoring issues

Targeted Central Review

Clinical experts assess flagged ratings of concern

Human review of flagged ratings

Final Quality Determination

Central Reviewer provides final review outcome, remediation, and commentary (as applicable)

Final human-qualified reviewed output

Signant Reputation

Trusted clinical assessment expertise you rely on

100% Human-Verification

Expert reviewers maintain final authority on all flagged assessments

AI Speed & Efficiency

Rapid analysis covering 100% of study data to de-risk your assessments

Complete Data Confidence

Every assessment receives appropriate level of oversight for maximum data confidence

Signant Health's 25+ years of evidence generation generation experience

600+ sponsors and CROs trust, including all Top 20 pharma

Global network of 800+ expert clinical reviewers

Proven track record in CNS endpoint quality

Signant Health is the evidence generation company. We are focused on leveraging software, deep therapeutic and scientific knowledge, and operational expertise to consistently capture, aggregate, and reveal quality evidence for clinical studies across traditional, virtual, and hybrid trial models. For more than 25 years, over 600 sponsors and CROs of all sizes – including all Top 20 pharma – have trusted Signant solutions for remote and site-based eCOA, EDC, eConsent, RTSM, supply chain management, and data quality analytics.
Learn more at www.signanthealth.com.

Clinical Data Collection

Clinical IP Management

Patient Engagement

Clinical Data and Analytics

Clinical Consulting

Applications For

AI-Targeting of Rating Assessments

100% Coverage, 100% Human-Verified

Closing the coverage gap

A new standard for comprehensive data confidence

How it works

Data & A/V Capture

Data & A/V Capture

Transcription output to AI-targeting

Transcription output to AI-targeting

AI-Targeting

AI-Targeting

Targeted Central Review

Targeted Central Review

Final Quality Determination

Final Quality Determination

Data & A/V Capture

Transcription output to AI-targeting

AI-Targeting

Targeted Central Review

Final Quality Determination

Four pillars of data confidence

Signant Reputation

100% Human-Verification

AI Speed & Efficiency

Complete Data Confidence

Industry-leading CNS expertise

Ready to transform your assessment quality assurance strategy?

WHO IS SIGNANT HEALTH?