Driving Engagement in Large-Scale Vaccine Trial
Signant Health
Mar 17, 2022

This case study showcases how Signant collaborated with clinical trial payments solution provider Greenphire to support a major pharmaceutical company's vaccine trial involving 44,000+ participants across 150+ global sites.
The integration enabled daily data exchange between Signant's eCOA platform and Greenphire's payment system, delivering 30,000 weekly micropayments to participants.
Despite an accelerated five-week timeline, Signant successfully deployed their solution worldwide, including 8,000+ provisioned devices.
This partnership:
- Improved participant retention through strategic micropayments
- Reduced site workload
- Maintained high-quality data collection for up to two years post-vaccination
The eCOA data contributed to regulatory submissions that secured FDA authorization for the vaccine.