Introducing Signant Health

Take a significant step towards patient-centricity

The best technology succeeds in the background. Signant Health provides solutions that simplify every step of the patient journey to make it easier for people to participate in, and for sites and study teams to run, clinical trials. Signant unites eCOA, eConsent, Patient Engagement, IRT, Clinical Supplies and Endpoint Quality into the industry’s most comprehensive patient-centric suite – an evolution built on more than 20 years of proven clinical research technology. Our intense focus on the patient experience, deep therapeutic area expertise and global operational scale enable hundreds of sponsors and CROs (including all Top 20 pharma) to extend the reach of drug development, expand patient opportunities and improve data quality – helping them bring life-changing therapies to our families and communities around the world.

“We put patients at the center of clinical research. From eCOA, eConsent and Patient Engagement to Endpoint Quality and Clinical Supplies, we simplify their journey through clinical trials and simplify the work of the study teams and sites that support them. Built on technology with the power to move research more quickly and more precisely, we make it easier for you to change lives.”- Mike Nolte, CEO of Signant Health

Our History


CRF Bracket re-emerges as Signant Health, a unified patient technology organization focused on making it easier for sponsors and CROs to change lives.


The combined CRF Bracket grows more in 1st quarter together than either company achieved alone in 2018.


Genstar Capital acquired CRF Health and combined it with Bracket to become CRF Bracket and deliver industry-leading patient-centric technology to improve the speed, reliability and insight of clinical research.


Bracket releases CUBE™, a transformative interactive response technology (IRT) solution for the life sciences industry.


Bracket Acquires mProve Health to radically advance patient engagement in clinical trials


CRF Health achieves one million monthly patient interactions.


Bracket was created in 2011 through the merger of the Specialty Clinical Services and Clinical Technologies Group business units within United BioSource Corporation (UBC).


PharmaStar LLC, the predecessor to Bracket Global LLC, was founded.


CRF Health, formerly known as CRF Inc., was founded.